Ilminster'S branch of the Bristol and West bank will close on March 16.
Customers will be given the chance to transfer to another branch or use a central telephone service to do their banking.
Meanwhile, the bank has said wherever possible, it is committed to providing alternative employment for staff affected by branch closures.
Head of marketing and strategy for Bristol and West Financial Services, David Williams, said: "We've been through a lengthy consultation with regards to our branches.
"I'm sorry to say the branch in Ilminster will be closing on March 16."
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